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. 2021 Sep 6;75(1):e1120–e1127. doi: 10.1093/cid/ciab754

Table 2.

Absolute Risk of Hospitalization by 28 Days Following a Positive Test for SARS-CoV-2, Expressed as a Percentage

% (95% CI)
Comorbidities/Sex/Age group Wild-type Alpha
No comorbidities
 Females
  0 to <40 years .55 (.49–.61) .74 (.67–.82)
  40 to <55 years 1.45 (1.32–1.59) 1.96 (1.79–2.12)
  55 to <65 years 2.26 (2.03–2.48) 3.02 (2.73–3.32)
  65 to <75 years 4.16 (3.70–4.63) 5.54 (4.93–6.14)
  75 to <85 years 5.76 (4.95–6.57) 7.61 (6.56–8.65)
  ≥85 years 9.82 (7.97–11.67) 12.77 (10.44–15.09)
 Males
  0 to <40 years .84 (.75–.92) 1.13 (1.01–1.24)
  40 to <55 years 2.20 (2.01–2.39) 2.95 (2.71–3.19)
  55 to <65 years 3.39 (3.06–3.72) 4.52 (4.11–4.94)
  65 to <75 years 6.19 (5.51–6.86) 8.16 (7.31–9.00)
  75 to <85 years 8.47 (7.31–9.64) 11.07 (9.60–12.54)
  ≥85 years 14.11 (11.55–16.68) 18.07 (14.94–21.20)
One comorbidity
 Females
  0 to <40 years 1.02 (.88–1.15) 1.37 (1.19–1.55)
  40 to <55 years 2.67 (2.38–2.95) 3.57 (3.20–3.94)
  55 to <65 years 4.10 (3.67–4.53) 5.45 (4.90–6.01)
  65 to <75 years 7.43 (6.63–8.22) 9.74 (8.73–10.76)
  75 to <85 years 10.11 (8.82–11.41) 13.13 (11.50–14.77)
  ≥85 years 16.62 (13.84–19.40) 21.09 (17.73–24.46)
 Males
  0 to <40 years 1.54 (1.35–1.74) 2.08 (1.81–2.34)
  40 to <55 years 4.00 (3.59–4.41) 5.32 (4.80–5.84)
  55 to <65 years 6.10 (5.50–6.70) 8.04 (7.29–8.79)
  65 to <75 years 10.82 (9.74–11.90) 14.02 (12.69–15.35)
  75 to <85 years 14.51 (12.75–16.28) 18.55 (16.40–20.70)
  ≥85 years 23.05 (19.46–26.65) 28.64 (24.47–32.81)
Two or more comorbidities
 Females
  0 to <40 years 1.63 (1.39–1.87) 2.19 (1.87–2.51)
  40 to <55 years 4.21 (3.68–4.75) 5.60 (4.90–6.30)
  55 to <65 years 6.41 (5.64–7.18) 8.44 (7.46–9.43)
  65 to <75 years 11.34 (10.10–12.59) 14.67 (13.11–16.22)
  75 to <85 years 15.18 (13.41–16.95) 19.36 (17.18–21.54)
  ≥85 years 23.99 (20.52–27.46) 29.72 (25.68–33.75)
 Males
  0 to <40 years 2.46 (2.10–2.81) 3.29 (2.83–3.76)
  40 to <55 years 6.26 (5.51–7.01) 8.25 (7.29–9.20)
  55 to <65 years 9.40 (8.36–10.43) 12.24 (10.94–13.53)
  65 to <75 years 16.17 (14.56–17.78) 20.55 (18.61–22.50)
  75 to <85 years 21.21 (18.93–23.48) 26.51 (23.82–29.19)
  ≥85 years 32.12 (27.93–36.31) 38.79 (34.16–43.41)

Abbreviations: CI, confidence interval; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.