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. 2021 Jun 3;80(11):1410–1418. doi: 10.1136/annrheumdis-2021-220097

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Forest plot of country-specific hazard ratios for TNFi discontinuation at 12 months comparing TNFi and csDMARD co-medication with TNFi monotherapy, ordered by overall TNFi retention rate per country. Adjusted for baseline age, sex, calendar year, DAS28 and disease duration. Combined results are not presented due to significant heterogeneity. Data from Romania are not presented due to <5 patients with monotherapy. csDMARDs, conventional synthetic disease-modifying anti-rheumatic drugs; DAS28, Disease Activity Score with 28 joints; TNFi, tumour necrosis factor inhibitors.