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. 2021 Jul 31;92(11):1222–1230. doi: 10.1136/jnnp-2021-326337

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.

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Longitudinal changes in the difference between spinal cord injury (SCI) patients' standardised white matter (WM) and grey matter (GM) areas over time at C2/C3 and in the lumbar enlargement (LE). For each patient with SCI, the standardised WM area is calculated by subtracting the average WM area in controls and dividing the result by the SD of WM area across controls (same approach for GM area). Dashed lines represent evolution in individual subjects, while the solid line represents the quadratic fit.