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Percentage of time above the predicted MIC after a single dose of meropenem/piperacillin/tazobactam after intravenous 1-h infusion administration at 200/300/200 mg/kg to healthy New Zealand White rabbits over a 4-h interval
| Drug (dosage [mg/kg]) | %T>MIC over a 4-h interval at MIC (μg/ml) of: |
|||
|---|---|---|---|---|
| 1 | 2 | 4 | 8 | |
| Meropenem (200) | 94 | 75 | 73 | 69 |
| Piperacillin (300) | 83 | 74 | 71 | 68 |
| Tazobactam (200) | 94 | 86 | 75 | 74 |
