. 2021 Oct 18;65(11):e01093-21. doi: 10.1128/AAC.01093-21

TABLE 1.

Pooled MIC distributions of three azoles for prevalent and nonprevalent Candida spp. determined by the commercial Etest method^a

Species^b	No. of labs	No. of isolates	No. of isolates with MIC (μg/ml) of^c
Species^b	No. of labs	No. of isolates	≤0.002	0.004	0.008	0.016	0.03	0.06	0.125	0.25	0.5	1	2	4	8	16	32	64	128	≥256
Fluconazole
C. albicans	18	17,242				27	94	758	4,362	7,226	3,138	948	318	109	38	47	27	18	12	120
C. glabrata	20	5,129				4	2	3	9	17	39	93	215	433	709	1,199	927	385	147	947
C. parapsilosis	20	2,947				4	16	51	236	663	866	627	244	72	39	32	13	7	5	72
C. tropicalis	19	2,214				2	4	9	34	200	619	772	378	79	35	20	16	11	2	33
C. krusei^d	15	1,122									4	4	5	14	51	188	260	62	31	405
C. kefyr	14	933				1	10	71	239	360	204	28	8	1	3	1	1		1	6
C. lusitaniae	15	519				5	11	30	90	159	115	46	16	3	5	5	10	6	3	15
C. guilliermondii	9	257								3	14	39	58	61	36	16	7	8	4	11
C. dubliniensis	3	244				2	2	37	92	63	28	7	8	3			2
Posaconazole
C. albicans	14	2,085	7	50	348	846	575	157	47	19	15	11	2	1			7^e
C. glabrata^d	10	740			4	6	5	15	22	31	68	105	91	86	44	37	226
C. tropicalis	11	384	2		22	67	119	88	40	29	8	4	2		2		1^e
C. parapsilosis	4	162	1	7	26	51	37	23	9	3	2			1			2^e
Voriconazole
C. albicans	19	10,806	522	2,544	3,988	2,355	795	280	124	63	43	20	11	10	2	5	44^e
C. glabrata^d	16	3,514		9	14	36	112	349	780	786	446	204	135	140	92	121	290^e
C. parapsilosis	14	1,674	20	101	237	358	382	287	152	58	25	16	21	12	1		4^e
C. tropicalis	18	1,639	3	10	27	168	407	538	334	66	43	16	7	4	3	3	9^e
C. krusei	16	1,133		1	1	4	11	64	197	390	340	81	24	12	4	2	2^e
C. kefyr	16	672	38	105	240	206	61	9	4	3	4		1	1
C. lusitaniae	13	355	34	74	152	54	11	6	10	6	6	1		1
C. guilliermondii	11	275		1	4	4	47	76	58	29	16	13	8	3		2	14^e

MICs determined by the commercial bioMérieux Etest method according to the manufacturer’s instructions (13).

C. guilliermondii (Meyerozyma guilliermondii), C. kefyr (Kluyveromyces marxianus), C. krusei (Pichia kudriavzevii), C. lusitaniae (Clavispora lusitaniae), and the complexes of C. glabrata and C. parapsilosis.

The highest number in each row (showing the most frequently obtained MIC or the mode) is in boldface.

ECV was not defined for posaconazole and C. glabrata due to asymmetry in the aggregated MIC distribution.

Values ≥32 μg/ml.