TABLE 5.
Multivariate logistic regression analysis of factors potentially associated with either the S450L or L430P rpoB mutation
| Characteristic | Multivariate OR (95% confidence interval) for rpoB mutationa |
|
|---|---|---|
| S450L | L430P | |
| Sex | ||
| Female | 1.09 (0.83–1.42) | 0.46 (0.23–0.95) |
| Male | 1.0 | 1.0 |
| Age (yrs) | ||
| 0–24 | 1.0 | 1.0 |
| 25–34 | 1.14 (0.76–1.70) | 0.61 (0.22–1.65) |
| 35–44 | 1.03 (0.67–1.57) | 1.53 (0.57–4.08) |
| 45+ | 1.26 (0.80–2.01) | 0.57 (0.17–1.91) |
| Drug resistance profile | ||
| MDR | 5.03 (3.66–6.85) | 1.0 |
| RMR | 1.0 | 12.84 (6.33–26.03) |
| HIV status | ||
| Negative | 1.0 | 1.0 |
| Positive | 0.88 (0.64–1.22) | 0.70 (0.32–1.52) |
| Unknown | 1.37 (0.42–4.43) | 3.06 (0.32–29.01) |
| Previous TB treatment | ||
| No | 1.0 | 1.0 |
| Yes | 1.06 (0.80–1.42) | 0.40 (0.20–0.79) |
| Unknown | 1.44 (0.50–4.12) | |
| Yr diagnosed | ||
| 2008–2012 | 1.0 | 1.0 |
| 2013–2017 | 0.82 (0.63–1.06) | 1.16 (0.60–2.26) |
a
Boldface indicates statistical significance.