Table 2. Probability of Having a Titer below Different Neutralizing Antibody Titers at 175 Days after Receipt of the Second Vaccine Dose, According to Sex and Age.
| Sex and Titer | Probability among Healthy Persons (95% CI)* |
Probability among Persons with BMI ≥30 (95% CI) |
Probability among Persons with Immunosuppression (95% CI)† |
||||||
|---|---|---|---|---|---|---|---|---|---|
| 18 to <45 Yr | 45 to <65 Yr | ≥65 Yr | 18 to <45 Yr | 45 to <65 Yr | ≥65 Yr | 18 to <45 Yr | 45 to <65 Yr | ≥65 Yr | |
| percent | |||||||||
| Female sex | |||||||||
| <16 | 0.02 (0.02–0.04) | 0.05 (0.04–0.07) | 0.06 (0.04–0.09) | 0.01 (0.01–0.02) | 0.03 (0.02–0.04) | 0.04 (0.02–0.06) | 0.18 (0.10–0.29) | 0.28 (0.17–0.41) | 0.30 (0.18–0.45) |
| <32 | 0.09 (0.07–0.11) | 0.15 (0.12–0.18) | 0.17 (0.13–0.22) | 0.06 (0.04–0.08) | 0.10 (0.08–0.13) | 0.12 (0.08–0.17) | 0.38 (0.25–0.52) | 0.51 (0.36–0.65) | 0.53 (0.38–0.68) |
| <64 | 0.23 (0.19–0.27) | 0.34 (0.29–0.39) | 0.36 (0.30–0.44) | 0.16 (0.12–0.21) | 0.26 (0.21–0.31) | 0.28 (0.21–0.36) | 0.62 (0.47–0.75) | 0.73 (0.60–0.84) | 0.75 (0.62–0.86) |
| <128 | 0.45 (0.40–0.50) | 0.58 (0.53–0.62) | 0.60 (0.53–0.68) | 0.36 (0.30–0.42) | 0.48 (0.42–0.54) | 0.51 (0.42–0.60) | 0.82 (0.70–0.90) | 0.89 (0.80–0.95) | 0.90 (0.82–0.96) |
| <256 | 0.68 (0.64–0.73) | 0.79 (0.75–0.83) | 0.81 (0.75–0.86) | 0.60 (0.53–0.66) | 0.72 (0.66–0.76) | 0.74 (0.66–0.80) | 0.93 (0.87–0.97) | 0.97 (0.93–0.99) | 0.97 (0.93–0.99) |
| Male sex | |||||||||
| <16 | 0.04 (0.02–0.06) | 0.11 (0.08–0.16) | 0.15 (0.10–0.21) | 0.02 (0.01–0.04) | 0.08 (0.05–0.11) | 0.10 (0.06–0.16) | 0.24 (0.12–0.38) | 0.44 (0.28–0.60) | 0.50 (0.34–0.67) |
| <32 | 0.12 (0.08–0.18) | 0.28 (0.21–0.34) | 0.34 (0.25–0.42) | 0.08 (0.05–0.13) | 0.20 (0.15–0.26) | 0.25 (0.18–0.34) | 0.45 (0.29–0.62) | 0.67 (0.52–0.81) | 0.73 (0.58–0.85) |
| <64 | 0.29 (0.21–0.38) | 0.50 (0.43–0.58) | 0.57 (0.48–0.66) | 0.22 (0.14–0.30) | 0.41 (0.32–0.49) | 0.48 (0.38–0.58) | 0.68 (0.53–0.82) | 0.85 (0.74–0.93) | 0.88 (0.79–0.95) |
| <128 | 0.52 (0.42–0.62) | 0.73 (0.67–0.79) | 0.78 (0.71–0.85) | 0.43 (0.33–0.53) | 0.65 (0.57–0.72) | 0.71 (0.62–0.79) | 0.86 (0.75–0.94) | 0.95 (0.90–0.98) | 0.96 (0.92–0.99) |
| <256 | 0.75 (0.66–0.82) | 0.89 (0.85–0.92) | 0.92 (0.88–0.95) | 0.66 (0.57–0.76) | 0.84 (0.78–0.89) | 0.88 (0.82–0.92) | 0.95 (0.90–0.98) | 0.99 (0.97–0.997) | 0.99 (0.98–0.998) |
*
Healthy persons were defined as participants without hypertension, diabetes, dyslipidemia, heart disease, lung disease, liver disease, immunosuppression, or autoimmune disease and with a BMI of less than 30.
†
Immunosuppression included organ transplantation, biologic therapy, chemotherapy, glucocorticoids, splenectomy, and human immunodeficiency virus infection.