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. 2021 Oct 4;12:717069. doi: 10.3389/fendo.2021.717069

Table 2.

Odds ratio (95% CI) for cardiovascular disease risks according to age at diagnosis of diabetes.

Age at diagnosis of diabetes (years)
≥60 50-59 40-49 18-39 Per 5-years earlier
Cardiovascular disease, case (%) 1337 (20.20) 1475 (15.01) 692 (11.34) 149 (10.54)
 Model 1 1.00 (reference) 1.21 (1.10-1.33) 1.28 (1.13-1.46) 1.46 (1.19-1.79) 1.09 (1.07-1.12)
 Model 2 1.00 (reference) 1.31 (1.18-1.46) 1.45 (1.26-1.67) 1.61 (1.28-2.02) 1.12 (1.09-1.16)
 Model 3 1.00 (reference) 1.33 (1.19-1.48) 1.52 (1.31-1.75) 1.72 (1.36-2.17) 1.14 (1.11-1.18)
Stroke, case (%) 350 (5.29) 365 (3.71) 174 (2.85) 37 (2.62)
 Model 1 1.00 (reference) 1.24 (1.04-1.47) 1.39 (1.11-1.76) 1.56 (1.07-2.28) 1.09 (1.04-1.14)
 Model 2 1.00 (reference) 1.26 (1.05-1.52) 1.42 (1.11-1.82) 1.50 (0.99-2.28) 1.10 (1.05-1.15)
 Model 3 1.00 (reference) 1.26 (1.05-1.52) 1.47 (1.14-1.89) 1.61 (1.05-2.45) 1.11 (1.06-1.17)
Myocardial infarction, case (%) 124 (1.87) 137 (1.39) 84 (1.38) 20 (1.42)
 Model 1 1.00 (reference) 1.15 (0.88-1.52) 1.49 (1.05-2.11) 1.77 (1.03-3.02) 1.13 (1.06-1.21)
 Model 2 1.00 (reference) 1.26 (0.94-1.71) 1.59 (1.09-2.32) 2.22 (1.26-3.91) 1.18 (1.09-1.27)
 Model 3 1.00 (reference) 1.25 (0.92-1.69) 1.52 (1.03-2.24) 2.14 (1.21-3.79) 1.17 (1.08-1.26)
Coronary heart disease, case (%) 1021 (15.43) 1142 (11.62) 525 (8.60) 113 (8.00)
 Model 1 1.00 (reference) 1.20 (1.07-1.33) 1.23 (1.06-1.41) 1.38 (1.09-1.74) 1.08 (1.05-1.11)
 Model 2 1.00 (reference) 1.32 (1.17-1.48) 1.43 (1.22-1.67) 1.54 (1.19-2.00) 1.12 (1.08-1.15)
 Model 3 1.00 (reference) 1.35 (1.20-1.52) 1.49 (1.27-1.75) 1.65 (1.27-2.15) 1.13 (1.10-1.17)

Model 1, adjusted for age and sex; Model 2: adjusted for age, sex, education, smoking status, drinking status, physical activity, healthy dietary, body mass index; Model 3, further adjusted for systolic blood pressure, total cholesterol, triglycerides and HbA1c.