Table 3.
Association between age at diagnosis of diabetes and cardiovascular disease risk by BMI categories.
| Cardiovascular disease | Stroke | Myocardial infarction | Coronary heart disease | |||||
|---|---|---|---|---|---|---|---|---|
| Case (%) | OR (95%CI) | Case (%) | OR (95%CI) | Case (%) | OR (95%CI) | Case (%) | OR (95%CI) | |
| BMI< 24kg/m2 | ||||||||
| ≥60 | 366 (16.34) | 1.00 (reference) | 107 (4.78) | 1.00 (reference) | 36 (1.61) | 1.00 (reference) | 270 (12.05) | 1.00 (reference) |
| 50-59 | 399 (11.50) | 1.29 (1.06-1.57) | 107 (3.08) | 1.02 (0.73-1.41) | 27 (0.78) | 0.83 (0.46-1.51) | 304 (8.76) | 1.39 (1.11-1.74) |
| 40-49 | 175 (7.87) | 1.30 (1.002-1.69) | 47 (2.11) | 1.09 (0.70-1.70) | 17 (0.76) | 0.99 (0.46-2.13) | 128 (5.75) | 1.29 (0.96-1.75) |
| 18-39 | 49 (8.55) | 1.81 (1.21-2.69) | 10 (1.75) | 1.01 (0.46-2.23) | 5 (0.87) | 1.70 (0.58-4.98) | 38 (6.63) | 1.89 (1.20-2.96) |
| Per 5-years earlier | 1.09 (1.03-1.15) | 1.01 (0.92-1.10) | 1.09 (0.95-1.26) | 1.10 (1.03-1.16) | ||||
| BMI 24-27.9 kg/m2 | ||||||||
| ≥60 | 614 (20.87) | 1.00 (reference) | 163 (5.54) | 1.00 (reference) | 59 (2.01) | 1.00 (reference) | 462 (15.70) | 1.00 (reference) |
| 50-59 | 684 (15.91) | 1.34 (1.15-1.56) | 167 (3.88) | 1.37 (1.04-1.80) | 74 (1.72) | 1.33 (0.86-2.06) | 530 (12.33) | 1.35 (1.14-1.61) |
| 40-49 | 325 (12.07) | 1.49 (1.21-1.84) | 86 (3.19) | 1.63 (1.13-2.35) | 46 (1.71) | 1.66 (0.95-2.90) | 237 (8.80) | 1.39 (1.10-1.76) |
| 18-39 | 59 (10.55) | 1.53 (1.07-2.19) | 16 (2.86) | 1.90 (1.02-3.54) | 8 (1.43) | 2.01 (0.84-4.81) | 46 (8.23) | 1.49 (1.003-2.23) |
| Per 5-years earlier | 1.14 (1.09-1.19) | 1.13 (1.05-1.22) | 1.18 (1.06-1.32) | 1.13 (1.07-1.18) | ||||
| BMI ≥ 28kg/m2 | ||||||||
| ≥60 | 357 (24.86) | 1.00 (reference) | 80 (5.57) | 1.00 (reference) | 29 (2.02) | 1.00 (reference) | 289 (20.13) | 1.00 (reference) |
| 50-59 | 392 (19.04) | 1.44 (1.16-1.79) | 91 (4.42) | 1.45 (0.97-2.16) | 36 (1.75) | 1.74 (0.94-3.24) | 308 (14.96) | 1.40 (1.11-1.77) |
| 40-49 | 192 (16.20) | 1.99 (1.48-2.68) | 41 (3.46) | 1.78 (1.03-3.08) | 21 (1.77) | 2.13 (0.95-4.81) | 160 (13.50) | 2.12 (1.54-2.91) |
| 18-39 | 41 (14.59) | 2.30 (1.45-3.67) | 11 (3.91) | 2.30 (1.003-5.29) | 7 (2.49) | 3.33 (1.10-10.10) | 29 (10.32) | 1.96 (1.16-3.31) |
| Per 5-years earlier | 1.24 (1.17-1.33) | 1.24 (1.12-1.38) | 1.25 (1.07-1.45) | 1.22 (1.14-1.30) | ||||
Adjusted for age, sex, education, smoking status, drinking status, physical activity, healthy dietary, systolic blood pressure, total cholesterol, triglycerides and HbA1c. P for interaction for cardiovascular disease = 0.0457; p for interaction for stroke = 0.0205; p for interaction for myocardial infarction= 0.1931; p for interaction for coronary heart disease = 0.1568. BMI, body mass index.