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. 2021 Oct 12;12(21):2177–2187. doi: 10.18632/oncotarget.28069

Figure 3. Quantitative TIL scores in primary and recurrent glioblastoma.

Figure 3

Density of CD3+, CD8+, CD4+ and PD-1+ TILs was calculated for each case and compared between primary and recurrent groups. No difference was seen in overall CD3+ TIL density (p = 0.191; A) CD8+ TILs were present at significantly higher density in recurrent tumours compared to primary tumours (p = 0.040; B). No differences were seen in CD4+ TIL density (p = 0.607; C) or PD-1+ TIL density (p = 0.070; D). Bars represent median score. PRIM: primary tumour, REC: recurrent tumour.