Table 5:
Conditions for staining yeast mitochondria with vital dyes
Dye | [Stock]1 | Staining conditions | |
---|---|---|---|
[Dye] | Incubation | ||
DiOC6(Riezman et al., 1983)2 | 17.5 mM | 17.5 nM | 15 min RT |
DASPMI3 | 1 mg/ml in ethanol | 10–100 μg/ml | 30 min RT |
Rhodamine 1234 | 10 mg/ml in DMSO5 | 5–10 μg/ml | 15–30 min RT |
MitoTracker6 | 1 mM in DMSO5 | 100 nM | 30 min RT |
DAPI | 1 mg/ml in H2O | 0.1 μg/ml | 15 min RT |
All stock solutions should be stored in the dark.
(Skowronek et al., 1990); Broad emission range; not recommended for green/red double-label studies.
DMSO can be toxic and inhibits partitioning of the dye into the aqueous environment of the cells. If DMSO is the solvent, use a stock concentration that is at least 100X.