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. 2021 Oct 11;48(6):213. doi: 10.3892/ijmm.2021.5046

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Copyright: © Virdis et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effects of tomentosin on cell cycle progression in RPMI-8226 cells. (A) Histograms show cell cycle profiles of tomentosin-treated RPMI-8226 cells. x-axis and y-axis correspond to DNA content and fraction of events, respectively. (B) The multiple myeloma cells treated with tomentosin 25 µM or vehicle solution (DMSO 0.05%) for 6, 8, 12, 18 and 24 h were blocked in the G2/M phase. Two-way ANOVA and Tukey's post hoc test were applied for the statistical analysis of the cell cycle. The bars represent the mean ± SD of the percentage of three independent experiments (with a P<0.05). ^*P≤0.0338; ^**P≤0.0037, ^***P≤0.0001.