Table 1:

Midazolam increases evoked IPSCs (eIPSCs)

Vehicle (DMSO)
		Baseline (raw values)		Steady-state (raw values)			Normalized Values
	n	Charge (pA*ms)	Amp (pA)	Charge (pA*ms)	Amp (pA)	Charge (pA*ms)		Amplitude (pA)
	10	−4.4 ± 0.4	−120 ± 13	−4.6 ± 0.3	−105 ± 9	108 ± 7		95 ± 7
Midazolam
		Baseline (raw values)		Steady-state (raw values)			Normalized Values
Conc (μM)	n	Charge (pA*ms)	Amp (pA)	Charge (pA*ms)	Amp (pA)	Charge (pA*ms)	p-value Charge	Amplitude (pA)	p-value Amplitude
0.3	11	−7.0 ± 1.3	−170 ± 26	−8.6 ± 0.9*	−180 ± 20	140 ± 14	0.052	120 ± 10	0.10
1	17	−9.0 ± 1.2	−180 ± 16	−13 ± 2.3**	−230 ± 30	160 ± 14#	0.019	130 ± 10#	0.039
10	6	−7.7 ± 1.2	−200 ± 29	−9.8 ± 1.1*	−190 ± 20	130 ± 12	0.090	110 ± 6.7	0.090
Diazepam
		Baseline (raw values)		Steady-state (raw values)			Normalized Values
Conc (μM)	n	Charge (pA*ms)	Amp (pA)	Charge (pA*ms)	Amp (pA)	Charge (pA*ms)	p-value Charge	Amplitude (pA)	p-value Amplitude
2	9	−8.0 ± 1.4	−230 ± 39	−13 ± 2.0**	−300 ± 58*	170 ± 14##	0.0010	130 ± 9.5##	0.0099

Raw values are averages of baseline and steady-state values from eIPSCs. Values shown are mean ± SEM. Data were collected and analyzed as described in Figure 1. Steady-state values are significantly different in the steady state period than in baseline if labelled (paired Student’s t-test, * p < 0.05, ** p < 0.01). Normalized values for midazolam and diazepam are significantly different in comparison to vehicle control (one-way ANOVA, ^# p < 0.05, ^## p < 0.01). p-values are shown for normalized drug conditions compared to vehicle conditions.