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. 2021 Sep 13;36(11):2883–2890. doi: 10.1093/humrep/deab218

Table I.

Overview of the characteristics of the COVID-19 infection and medically assisted reproduction techniques used for the 105 cases reported in total and subdivided according to the outcome of the pregnancy.

COVID-19 affected MAR pregnancies (n = 105) Characteristics according to outcome
Live births (n = 67) Miscarriage (n = 10) Stillbirth (n = 2) Maternal death (n = 1)
Diagnosis COVID-19
 RT-PCR 97 (92.4%) 60 (89.5%) 9 (90.0%) 2 (100%) 1 (100%)
 Antibody 3 (2.9%) 3 (4.5%) 0 0 0
 Other 5 (4.8%) 4 (6.0%) 1 (10.0%) 0 0
Time of diagnosis
 During the MAR treatment (including 15 days after embryo transfer) 11 (10.5%) 2 (3.0%) 3 (30.0%) 0 0
 First trimester 32 (30.5%) 11 (16.4%) 7 (70.0%) 0 1 (100%)
 Second trimester 21 (20.0%) 14 (20.9%) 0 2 (100%) 0
 Third trimester (including delivery) 41 (39.0%) 40 (59.7%) 0 0 0
Symptoms
 Asymptomatic 33 (31.4%) 24 (35.8%) 3 (30.0%) 0 0
 Fever 42 (40.0%) 28 (41.8%) 4 (40.0%) 1 (50.0%) 1 (100%)
 Cough 37 (35.2%) 23 (34.3%) 3 (30.0%) 2 (100%) 1 (100%)
 Anosmia 30 (28.6%) 18 (26.9%) 3 (30.0%) 1 (50.0%) 0
 Ageusia 15 (14.3%) 9 (13.4%) 4 (40.0%) 0 0
 Gastrointestinal symptoms 12 (11.4%) 8 (11.9%) 0 0 0
 Other 19 (17.3%) 15 (22.4%) 2 (20.0%) 0 0
Hospitalization
 None 72 (68.6%) 38 (56.7%) 10 (100%) 1 (50.0%) 0
 General ward 28 (26.7%) 25 (37.3%) 0 1 (50.0%) 0
 ICU 2 (1.9%) 2 (3.0%) 0 0 0
 Respiratory support 3 (2.9%) 2 (3.0%) 0 0 1 (100%)
MAR technique
 ART 67 (63.8%) 38 (56.7%) 8 (80.0%) 0 1 (100%)
 Ovulation induction, with or without IUI 38 (36.2%) 29 (43.3%) 2 (20.0%) 2 (100%) 0
Maternal age
 Mean ± SD age (years)1 33.7 ± 6.1a 33.1 ± 1.7b 38.0 ± 2.6c 34.0d 25.0e

Data are represented as numbers and percentages.

COVID-19, coronavirus disease 2019; ICU, intensive care unit; MAR, medically assisted reproduction; RT-PCR, real-time PCR.

1

Data available for 81a, 58b, 7c, 1d and 1e cases.