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. 2021 Sep 13;36(11):2883–2890. doi: 10.1093/humrep/deab218

Table III.

Characteristics of the COVID-19 infection and medically assisted reproduction techniques used for the 67 deliveries (72 neonates) subdivided between term and preterm deliveries.

Term birth (≥37 weeks) Preterm birth (<37 weeks)
n = 54 n = 13
Diagnosis COVID-19
 RT-PCR 49 (90.7%) 11 (84.6%)
 Antibody 3 (5.6%) 0
 Other 2 (3.7%) 2 (15.4%)
Time of diagnosis

 During the MAR treatment

(including 15 days after embryo transfer)

2 (3.7%) 0
 First trimester 10 (18.5%) 1 (7.7%)
 Second trimester 13 (24.1%) 1 (7.7%)
 Third trimester (including delivery) 29 (53.7%) 11 (84.6%)
Symptoms
 Asymptomatic 19 (35.2%) 5 (38.5%)
 Fever 22 (40.7%) 6 (46.2%)
 Cough 20 (37.0%) 3 (23.1%)
 Anosmia 16 (29.6%) 2 (15.4%)
 Ageusia 7 (13.0%) 2 (15.4%)
 Gastrointestinal symptoms 6 (11.1%) 2 (15.4%)
 Other 11 (20.4%) 4 (30.8%)
Hospitalization
 None 33 (61.1%) 5 (38.5%)
 General ward 17 (31.5%) 8 (61.5%)
 ICU 2 (3.7%) 0
 Respiratory support 2 (3.7%) 0
MAR technique
 ART 30 (55.6%) 8 (61.5%)
 Ovulation induction, with or without IUI 24 (44.4%) 5 (38.5%)
Maternal age
 (Mean ± SD) (years)1 33.5 ± 6.5a 31.7 ± 6.4b
Twin pregnancies 2 (3.7%) 3 (23.1%)
Mode of delivery
 Vaginal delivery 20 (37.0%) 5 (38.5%)
 Caesarean section 33 (61.1%) 8 (61.5%)
 Unknown 1 (1.9%) 0
Neonates Neonates
n = 56 n = 16
Neonatal complications
 None 53 (94.6%) 9 (56.3%)
 Respiratory symptoms 1 (1.8%) 4 (25.0%)
 Fever 0 0
 Other complications 2 (3.6%) 3 (18.8%)
Hypoxia (1), weight loss (1) All related to prematurity
Birth weight
 Normal (>2500 g) 53 (94.6%) 6 (37.5%)
 Low (<2500 g) 3 (5.4%) 7 (43.8%)
 Very low (<1500 g) 0 2 (12.5%)
 Extremely low (<1000 g) 0 1 (6.3%)
COVID-19
 Not tested 31 (55.4%) 7 (43.8%)
 SARS-CoV-2 positive (RT-PCR) 0 2 (12.5%)
 SARS-CoV-2 negative (RT-PCR)

Data are represented as numbers and percentages.

COVID-19, coronavirus disease 2019; ICU, intensive care unit; MAR, medically assisted reproduction; RT-PCR, real-time PCR; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.

1

Data available for 46a and 12b cases.