Table 1.

Mediation Results for Models with Negative Symptoms as Proposed Mediator Between Neurocognition and Work Functioning

Path	β	B	SE	p-value
Cross-Sectional Model (n = 277)
Indirect effect with processing speed: z = .01, SE = .01, 95% CI [.002, .03]
Indirect effect with general knowledge: z = .01, SE = .01, 95% CI [−.01, .02]
2-year processing speed → 2-year work functioning	.21	.02	.01	.01
2-year general knowledge → 2-year work functioning	.12	.03	.02	.07
2-year negative symptoms → 2-year poverty of speecha,b	.78	1.00	--	--
2-year negative symptoms → 2-year flat affecta	.58	1.15	.20	< .001
2-year negative symptoms → 2-year psychomotor retardationa	.75	.48	.07	< .001
2-year processing speed → 2-year negative symptoms	−.47	−.03	.01	< .001
2-year general knowledge → 2-year negative symptoms	−.03	−.01	.01	.71
2-year negative symptoms → 2-year work functioning	−.24	−.48	.20	.02
2-year positive symptoms → 2-year work functioning	−.18	−.34	.12	.004
Prospective Model - 7.5-year work functioning (n = 277)c
Indirect effect with processing speed: z = .002, SE = .003, 95% CI [−.002, .01]
Indirect effect with general knowledge: z = .004, SE = .005, 95% CI [−.004, .02]
2-year processing speed → 7.5-year work functioning	.37	.04	.01	< .001
2-year general knowledge → 7.5-year work functioning	−.002	−.001	.02	.98
4.5-year negative symptoms → 4.5-year poverty of speecha,b	.98	1.00	--	--
4.5-year negative symptoms → 4.5-year flat affecta	.70	.77	.11	< .001
4.5-year negative symptoms → 4.5-year psychomotor retardationa	.61	.32	.05	< .001
2-year processing speed → 4.5-year negative symptoms	−.10	−.01	.01	.29
2-year general knowledge → 4.5-year negative symptoms	−.10	−.02	.02	.29
4.5-year negative symptoms → 7.5-year work functioning	−.14	−.20	.11	.07
2-year positive symptoms → 7.5-year work functioning	−.18	−.34	.13	.01

^aLoadings are for observed negative symptom subscales on the latent negative symptoms indicator

^bRegression weight set at 1

^c217 participants participated in the 4.5 year follow-up and 198 participated in the 7.5 year follow-up; FIML was used to estimate missing data.