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Toxicity of D-melittin peptide and micelles against a range of human and murine tumor cell lines. For DMM, the concentration is expressed as containing a peptide equivalent to free peptide.
| Viability IC50 (µM) | ||
|---|---|---|
| Cell line | D-melittin | DMM |
| 3T3 | 3.2 | 8.5 |
| A549 | 4.5 | 6.9 |
| CT26 | 2.2 | 11.6 |
| MDA-MB-435 WT | 3.5 | 30.1 |
| MDA-MB-435 DOX-R | 3.4 | 3.0 |
