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. 2021 Jun 10;35(11):6358–6365. doi: 10.1007/s00464-021-08567-y

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Target tissue temperature profile in two hIBUB organs (blue and red lines) during hPIPAC. The therapeutic phase begins at the end of the chemotherapy administration (spraying) phase. The infrared energy source restores and maintains the temperature of the target tissue within the desired therapeutic hyperthermia range (highlighted blue area) for the time needed (30 min) (Color figure online)