Table 2.

Differences in brain volumes between the NPSLE patients and the non-NPSLE patients

	NPSLE patients (n = 38)	Non-NPSLE patients (n = 117)	NPSLE vs non-NPSLE (B (95% CI))
White matter volume	473 ± 55	482 ± 57	−11.5 (−23.5 to 0.6)
Grey matter volume	557 ± 62	560 ± 61	−8.3 (−20.3 to 3.6)
Total brain volume	1030 ± 110	1042 ± 111	−19.8 (−40.5 to 0.9)
WMH volume	1.08 (0.12–14.94)	0.60 (0.11–5.04)	0.67 (0.21 to 1.13)*

The second and third columns represent white matter, grey matter, total brain, and white matter hyperintensity (WMH) volume in ml expressed as means ± standard deviations or median (10–90% confidence intervals)

The fourth column represents B (95% confidence intervals) of the linear regression analyses on brain and WMH volumes in NPSLE patients versus non-NPSLE patients, adjusted for gender, age, and total intracranial volume. For the linear regression analysis, the WMH were multiplied by 1,000,000 and natural log transformed, because of non-normal distribution

*p < 0.05