Table 2. Cairo-Bishop classification for tumor lysis syndrome.

LTLS, laboratory tumor lysis syndrome; ULN, upper limit of normal.

Laboratory tumor lysis syndrome - abnormality in two or more
Metabolite or electrolyte	Diagnostic criteria
Uric acid	≥8 mg/dL or 25% increase from baseline
Potassium	≥6 mEq/L or 25% increase from baseline
Phosphorus	≥6.5 mg/dL (children), ≥4.5 mg/dL (adults), or 25% increase from baseline
Calcium	≥25% decrease from baseline
Clinical tumor lysis syndrome
LTLS and at least one of the following: (1) creatinine × 1.5 ULN (age >12 years or age-adjusted); (2) cardiac arrhythmia or sudden death; and (3) seizure