Table 2.
Univariate |
Multivariate model 1:Forcibly input a significant variable with a univariate |
Multivariate model 2: Input significant variables in univariates by stepwise method |
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n | PRC | SE | SPRC | t value | p value | PRC | SE | SPRC | t value | p value | VIF | PRC | SE | SPRC | t value | p value | VIF | |
Age (per 1 year) | 27 | −0.012 | 0.010 | −0.231 | −1.186 | 0.247 | – | – | ||||||||||
Gender (Female vs. Male) | 27 | 0.932 | 0.471 | 0.368 | 1.978 | 0.059 | – | – | ||||||||||
Severity of COVID-19 | 27 | – | – | |||||||||||||||
Mild | 6 | ref | ||||||||||||||||
Moderate | 19 | −0.899 | 0.572 | −0.336 | −1.572 | 0.129 | ||||||||||||
Severe | 2 | −1.382 | 0.998 | −0.296 | −1.386 | 0.179 | ||||||||||||
Comorbidity | 27 | 0.155 | 0.489 | 0.063 | 0.317 | 0.754 | – | – | ||||||||||
WBC (per 1000/μL) | 27 | −0.214 | 0.197 | −0.212 | −1.084 | 0.289 | – | – | ||||||||||
ALT (per 1U/L) | 27 | −0.039 | 0.011 | −0.567 | −3.444 | 0.002 | −0.013 | 0.010 | −0.190 | −1.285 | 0.214 | 1.610 | n.e. | |||||
CRP (per 1 mg/dl) | 27 | −0.190 | 0.029 | −0.792 | −6.486 | 0.000 | −0.108 | 0.050 | −0.441 | −2.176 | 0.042 | 3.037 | n.e. | |||||
Ferritin (per 100 ng/mL) | 24 | −0.222 | 0.035 | −0.805 | −6.361 | 0.000 | −0.091 | 0.063 | −0.328 | −1.444 | 0.164 | 3.800 | −0.222 | 0.035 | −0.805 | −6.361 | 0.000 | 1.000 |
D-dimer (per 1 μg/mL) | 24 | 0.079 | 0.149 | 0.113 | 0.533 | 0.599 | – | – | ||||||||||
Uric acid (per 1 mg/dL) | 25 | 0.000 | 0.177 | 0.000 | −0.002 | 0.998 | – | – | ||||||||||
eGFR (per 1 ml/min/1.73m2) | 27 | 0.010 | 0.014 | 0.136 | 0.687 | 0.498 | – | – |
PRC; Partial Regression Coefficient, SE; Standard error, SPRC; Standardized Partial Regression Coefficient, VIF; Variance Inflation Factor, ref: reference standard, n.e.; not entered.
dependent variable:"FPV blood level (trough value)" that has undergone logarithmic conversion.
Multivariate model 1: R2 = 0.729, Adjusted R2 = 0.688.
Multivariate model 2: R2 = 0.648, Adjusted R2 = 0.632.