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. 2021 Oct 18;11:20563. doi: 10.1038/s41598-021-99153-8

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Association of the CMR measures, CRFs and brain-PAD. For each model, the numbers on the x-axis represents the order of the different CMR and CRFs measures summarised in the legend, while the regression coefficient (the diamond shape represents the beta coefficient) values are reported in the y-axis along with their standard error. Grey color indicates non-significant association.