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. 2021 Oct 18;11:20598. doi: 10.1038/s41598-021-97842-y

Table 2.

Cluster information of different functional connectivity between the controls and the TGA patients.

Cluster size (mm3) Maximum t value MNI atlas coordinates
(location of maximum t-value)
x y z
Salience Network (↑ in TGA)
Fronto-parietal operculum (L) 2424 4.86 48 − 28 20
Anterior insular (R) 2032 4.55 38 0 10
Anterior insular (L) 896 4.5 − 36 − 4 8
Frontal operculum (L) 744 4.11 − 52 − 4 12
Superior frontal (L) 360 3.86 − 62 − 26 20
Default Mode Network (↓ in TGA)
Precunues(R) 1320 4.87 16 − 70 38
Angular gyrus(R) 728 3.71 44 − 60 44
Precuneus(L) 496 3.61 − 14 − 72 − 28
Precunues(R) 440 3.82 8 − 54 42
Central Executive Network (↑ in TGA)
Medial Prefrontal (L) 336 3.63 − 4 44 26

Significant difference of clusters in the default mode, salience and central executive network between the controls and TGA patients. Regions of decreased or increased connectivity in the TGA group were shown at the cluster-corrected P < 0.05.