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. Author manuscript; available in PMC: 2023 Sep 1.
Published in final edited form as: Biometrics. 2021 May 4;78(3):1233–1243. doi: 10.1111/biom.13475

Table 2.

Results from the CPCRA study

Model 1 Model 2
Variable Est SE p-value Est SE p-value
Longitudinal
Intercept 4.07 0.18 <0.0001 4.06 0.18 <0.0001
Treatment −0.08 0.11 0.47 −0.08 0.11 0.49
Year −0.79 0.10 <0.0001 −0.77 0.11 <0.0001
Gender 0.24 0.19 0.20 0.25 0.19 0.19
PrevOI −0.95 0.14 <0.0001 −0.94 0.14 <0.0001
Stratum 0.12 0.13 0.38 0.13 0.13 0.34
HgB 0.23 0.03 <0.0001 0.24 0.03 <0.0001
Treatment × Year −0.09 0.12 0.45 −0.10 0.12 0.43
Random Effect: Intercept 1.21 0.09 <0.0001 1.22 0.09 <0.0001
Random Effect: Slope 0.67 0.11 <0.0001 0.66 0.11 <0.0001
Random Effect Covariance −0.03 0.07 0.73 −0.02 0.07 0.77
σ2e 0.30 0.01 <0.0001 0.30 0.01 <0.0001
Survival
Treatment −0.26 0.19 0.17 −0.28 0.18 0.14
CD4 0.36 0.19 0.06 0.32 0.21 0.12
Shared Effect Intercept −0.92 0.24 0.0001 −0.71 0.31 0.02
Shared Effect Slope −0.75 0.30 0.01 −0.90 0.39 0.02
CD4×Shared Effect Intercept NA NA NA −0.06 0.06 0.29
CD4×Shared Effect Slope NA NA NA 0.09 0.09 0.33
Gender −0.19 0.32 0.55 −0.16 0.31 0.62
PrevOI 1.47 0.36 <0.0001 1.37 0.35 0.0001
Stratum −0.18 0.21 0.41 −0.20 0.21 0.34
HgB −0.50 0.08 <0.0001 −0.49 0.09 <0.0001