Fig. 2. Accuracy of 7 polygenic prediction methods across 14 UK Biobank quantitative traits.
We report results for P + T, LDpred, SBayesR, P + T-funct-LASSO, AnnoPred, LDpred-funct-inf and LDpred-funct. Dashed lines denote estimates of SNP-heritability. Numerical results are reported in Supplementary Table 14. Abbreviations: Red Blood Cell Distribution Width (RBD distribution width), forced expiratory volume in one second (FEV1), and forced vital capacity (FVC). Data points represent the prediction accuracy values obtained via block-jacknife over 200 genomic blocks. Source data are provided as a Source Data file.