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. 2021 Oct 18;11:534. doi: 10.1038/s41398-021-01653-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — We categorized the total sample into apathy− subgroup and apathy+ subgroup. A1, A2, C1, C2 Lower cognitive functions were significant in apathy+ individuals than their normal counterparts. A3, C3 Lower quality of life were significant in apathy+ individuals. B, D Higher CSF Aβ₄₂ (low statistical power) were significant in apathy+ individuals. Dots represented individuals’ clinical outcomes, with violin plots showing their median values and distributions. *p < 0.05, ***p < 0.001.