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. 2021 Oct 5;8:725298. doi: 10.3389/fmed.2021.725298

Table 2.

Multivariate logistic regression analysis for risk factors associated with bone metastasis in cervical patients.

Variables OR 95% CI P-value
Age* 0.99 0.99, 1.00 0.11
Race
Black
Other 0.95 0.64, 1.40 0.8
Unknown 0 0, 0 >0.9
White 1.08 0.85 0.5
Primary_site
Cervix uteri
Endocervix 0.74 0.53, 1.02 0.076
Exocervix 0.3 0.05, 0.99 0.1
Overlapping lesion of cervix uteri 0.67 0.25, 1.51 0.4
Grade
Gradel
Gradell 1.42 0.74, 3.00 0.3
Gradelll 1.95 1.04, 4.07 0.051
GradeIV 1.74 0.81, 4.01 0.2
Unknown 1.77 0.95, 3.70 0.1
Pathology
ADC
Others 1.11 0.81, 1.55 0.5
SCC 0.89 0.66, 1.21 0.4
SEER_historic
Distant
Localized 0 0, 0 >0.9
Regional 0 0, 0 >0.9
Unknown 0.03 0, 0.1 <0.001
Lymph_biopsy
>4
≤ 3 5.03 1.70, 14.6 0.003
Unknown 9.22 4.82, 20.5 <0.001
Brain_metastasis <0.001
No
Unknown 8.85 3.42, 25.0 <0.001
Yes 3.28 2.02, 5.29 <0.001
Liver_metastasis
No
Unknown 2.28 0.86, 5.72 0.085
Yes 2.66 2.10, 3.37 <0.001
Lung_metastasis
No
Unknown 1.77 0.85, 3.52 0.11
Yes 1.6 1.30, 1.97 <0.001
Distant_Lymph_metastasis
No
Unknown 0.02 0.03, 0.67 0.029
Yes 6.18 3.87, 9.84 <0.001
CS_tumor_size,cm
<5
≥5 0.84 0.04, 5.14 0.9
Unknown 0.98 0.79, 1.21 0.8

*Continuous variable. ADC, Adenocarcinoma; SCC, Squamous cell carcinoma.