Table 1.
Clinical data and laboratory data of participants.
| All | AHI <15 events/h | AHI ≥15 events/h | P-value | |
|---|---|---|---|---|
| n | 75 | 33 | 42 | |
| Age (years) | 39.21 ± 8.34 | 38.61 ± 7.67 | 39.69 ± 8.90 | 0.58 |
| BMI (kg/m2) | 26.68 ± 3.22 | 25.60 ± 3.00 | 27.53 ± 3.17 | <0.01 |
| Hypertension (n) | 26 | 5 | 21 | <0.01 |
| Current smokers (n) | 19 | 5 | 14 | 0.072 |
| Rhinitis (n) | 26 | 12 | 14 | 0.71 |
| Stage N1 (%/TST) | 7.72 ± 5.16 | 7.49 ± 4.56 | 7.90 ± 5.63 | 0.73 |
| Stage N2 (%/TST) | 41.46 ± 11.2 | 38.76 ± 10.37 | 43.58 ± 11.50 | 0.06 |
| Stage N3 (%/TST) | 25.31 ± 12.45 | 26.98 ± 10.23 | 24 ± 13.92 | 0.31 |
| Stage REM (%/TST) | 17.20 ± 6.11 | 17.91 ± 6.70 | 16.64 ± 5.62 | 0.38 |
| Stage Wake (%/TST) | 8.05 ± 7.15 | 8.57 ± 6.67 | 7.64 ± 7.57 | 0.58 |
| AI (events/h) | 8.4 (5, 14.6) | 6.3 (4.15, 9.2) | 12.35 (6.48, 21.65) | <0.01 |
| AHI (events/h) | 16.6 (5.90, 51.30) | 3.4 (0.8, 8.3) | 48 (25.58, 64.83) | <0.01 |
| ODI (events/h) | 15.50 (1.80, 47.30) | 1.5 (0.65, 4.95) | 41.3 (20.95, 61.65) | <0.01 |
| Mean SpO2 (%) | 96.33 ± 2.11 | 97.3 ± 1.36 | 95.57 ± 2.30 | <0.01 |
| LSpO2 (%) | 85.59 ± 7.90 | 91.55 ± 3.73 | 80.90 ± 7.10 | <0.01 |
| T90 (%) | 0.1 (0, 1.10) | 0 (0, 0) | 0.8 (0.275, 2.33) | <0.01 |
| HB (g/L) | 155.83 ± 11.26 | 155.15 ± 10.93 | 156.36 ± 11.62 | 0.65 |
| ALT (U/L) | 32 (20, 54) | 28 (19, 40.5) | 39 (25.5, 56) | 0.02 |
| Cr (μ mol/L) | 76.93 ± 9.60 | 79.30 ± 8.97 | 75.07 ± 9.78 | 0.058 |
| GLU (mmol/L) | 4.9 (4.7, 5.3) | 4.8 (4.5, 5.1) | 5.1 (4.8, 5.5) | <0.01 |
| HBA1C (%) | 5.4 (5.1, 5.6) | 5.2 (5.05, 5.5) | 5.5 (5.3, 5.6) | <0.01 |
| TG (mmol/L) | 1.46 (1.04, 2.39) | 1.14 (0.91, 1.89) | 1.72 (1.36, 3.33) | <0.01 |
| TC (mmol/L) | 4.81 ± 0.77 | 4.73 ± 0.78 | 4.87 ± 0.76 | 0.41 |
| LDLC (mmol/L) | 3.11 ± 0.72 | 3.12 ± 0.68 | 3.10 ± 0.76 | 0.88 |
| HDL (mmol/L) | 1.10 ± 0.26 | 1.17 ± 0.24 | 1.05 ± 0.26 | 0.03 |
| UA (μmol/L) | 405.80 ± 82.98 | 395.85 ± 71.94 | 413.62 ± 90.81 | 0.36 |
| hsCRP (mg/L) | 1.17 (0.69, 2.01) | 0.8 (0.5, 1.33) | 1.64 (0.85, 2.44) | <0.01 |
| TNF-α (pg/ml) | 7.2 (6, 8.8) | 6.6 (5.8, 8) | 7.9 (6.08, 9.23) | 0.07 |
| ET-1 (pg/ml) | 0.36 (0.26, 0.63) | 0.36 (0.21, 0.54) | 0.36 (0.26, 0.68) | 0.46 |
| VCAM (ng/ml) | 530.36 (461.35, 617.61) | 520.51 (451.62, 619.35) | 532.48 (477.84, 610.27) | 0.51 |
| VEGF (pg/ml) | 25.47 (19.88, 34.26) | 22.28 (17.09, 29.86) | 28.27 (21.28, 35.45) | 0.03 |
| AIx75 (%) | −4 (−14, 8) | −12 (−18.5, 0) | −1 (−8, 17.25) | <0.01 |
| RHI | 1.84 ± 0.48 | 1.78 ± 0.48 | 1.89 ± 0.48 | 0.32 |
Data presented as mean ± SD or the median with interquartile range. AI, arousal index; AHI, apnea hypopnea index; ALT, alanine transaminase; AIx75, augmentation Index@75 beats/minute; BMI, body mass index; Cr, Creatinine; ET-1, endothelin-1; GLU, glucose; HB, hemoglobin; HbA1C, hemoglobin A1C; HDL, high density lipoprotein; hsCRP, high sensitivity C reactive protein; LDLC, low density lipoprotein; ODI, oxygen desaturation index; LSpO2, lowest pulse arterial oxygen saturation; REM, rapid eye movement; RHI, reactive hyperaemia index; SpO2, oxygen saturation; T90, percentage of sleep time with oxygen saturation <90%; TC, total cholesterol; TG, triglyceride; TST, total sleep time; TNF-α, tumor necrosis factor alpha; UA, uric acid; VCAM, vascular cell adhesion molecule; VEGF, vascular endothelial growth factor.