Table 2.

Associations of the Included SNPs with Social Isolation (Exposure) and Osteoarthritis (Outcome)

SNP	EA	Chromosome Location	Social Isolation (Exposure)				Osteoarthritis (Outcome)
			EAF	β	SE	P	EAF	β	SE	P
rs12364432	A	11	0.347	−0.007	0.001	3.25×10−11	0.346	−0.001	0.001	0.160
rs13291079	C	9	0.425	−0.006	0.001	5.35×10−9	0.423	−0.001	0.001	0.110
rs2352075	C	2	0.117	0.009	0.001	4.40×10−10	0.118	0.003	0.001	2.30×10−3
rs4958586	A	5	0.632	0.006	0.001	1.01×10−8	0.632	0.000	0.001	0.550
rs599550	A	18	0.848	0.008	0.001	3.08×10−9	0.848	0.002	0.001	0.025

Abbreviations: SNP, single nucleotide polymorphism; EA, effect allele; EAF, effect allele frequency; SE, standard error.