Table 4.

Associations of the Included SNPs with Osteoarthritis (Exposure) and Social Isolation (Outcome)

SNP	EA	Chromosome Location	Osteoarthritis (Exposure)				Social Isolation (Outcome)
			EAF	β	SE	P	EAF	β	SE	P
rs10405617	G	19	0.664	−0.003	0.001	4.30×10−3	0.665	−0.001	0.001	0.601
rs12133235	C	1	0.421	0.003	0.001	1.20×10−8	0.422	−0.001	0.001	0.225
rs13107325	T	4	0.075	0.01	0.001	9.00×10−14	0.075	0.003	0.002	0.052
rs2290573	A	15	0.56	0.004	0.001	2.90×10−6	0.567	−0.001	0.001	0.448
rs3771501	G	2	0.524	−0.004	0.001	1.40×10−8	0.526	−0.001	0.001	0.195
rs75621460	A	19	0.027	0.013	0.002	1.20×10−6	0.026	−0.000	0.003	0.965

Abbreviations: SNP, single nucleotide polymorphism; EA, effect allele; EAF, effect allele frequency; SE, standard error.