Table 3.
Susceptibility of clinical isolated multidrug-resistant (MDR) pathogens to antibiotics, AS-hepc3(41-71), and AS-hepc3(48-56).
| Strain | Antibiotic resistance | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Amikacin | Ciprofloxacin | Gentamicin | Meropenem | Cefoperazone/Sulbactam | Tobramycin | Imipenem | Aztreonam | Cefepime | Levofloxacin | Piperacillin | Ceftazidime | Piperacillin/Tazobactam | AS-hepc3(41-71) (μM) | AS-hepc3(48-56) (μM) | |||
| MIC | MBC | MIC | MBC | ||||||||||||||
| QZ18050 | 16 | 16 | 16 | 16 | |||||||||||||
| QZ18106 | 16 | 32 | 32 | 32 | |||||||||||||
| QZ18109 | 8 | 16 | 8 | 16 | |||||||||||||
| QZ19121 | 8 | 16 | 8 | 16 | |||||||||||||
| QZ19122 | 8 | 16 | 8 | 16 | |||||||||||||
| QZ19123 | 8 | 8 | 8 | 8 | |||||||||||||
| QZ19124 | 8 | 16 | 8 | 16 | |||||||||||||
| QZ19125 | 8 | 32 | 8 | 16 | |||||||||||||
Bacteria susceptible, intermediate, or resistant to each antibiotic were shown as a green box, orange box, or red box, respectively. Gray boxes are shown if the susceptibility to agents in that class is not assessed. The experiment is performed in triplicate. QZ18050: MDR A. baumannii, QZ18106: MDR K. pneumoniae, QZ18109: MDR E. coli, QZ19121- QZ19125: MDR P. aeruginosa.