Fig. 1. Brain MRI showed a cytotoxic lesion of the corpus callosum (CLOCCs) after the first dose of mRNA vaccination (BNT162b). (A-B) Diffusion and ADC map showed a small oval-shaped restricted lesion of corpus callosal splenium. (C) Fluid-attenuated inversion- recovery (FLARE) image showed high signal intensity on the same lesion. (D) A lack of enhancement on T1 contrast-enhanced image (T1CE). (E-H) After 3 months, follow-up images of the same patient showed the resolution of previous lesions and no significant abnormalities without T1CE enhancement. The patient refused to receive the second dose of the mRNA vaccine.
