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. 2021 Jul 10;36(40):e286. doi: 10.3346/jkms.2021.36.e286

Table 1. Demographic and clinical features of previously reported myocarditis following coronavirus disease 2019 vaccination.

No. Reference No. of patients Sex, M:F Age, yr median (range) Sx (No. of patients) Histopathologic confirmation Outcome (No. of patients) Vaccine dose (No. of patients) Type of vaccine (No. of patients) Days from vaccination to Sx onset, median (range)
1 Montgomery et al.8 23 23:0 25 (20–51) Chest pain (23/23) Not done Resolved (23/23) 1st (3/23) BNT162b2-mRNA (7/23) 50 (12–96)a
2nd (20/23) mRNA-1273 (16/23)
2 Larson et al.5 8 8:0 28.5 (21–56) Chest pain (8/8) Endomyocardial biopsyb Resolved (8/8) 1st (1/8) BNT162b2-mRNA (5/8) 3 (2–4)
Fever (5/8) 2nd (7/8) mRNA-1273 (3/8)
3 Marshall et al.7 7 7:0 17 (14–19) Fever (5/7) Not done Resolved (7/7) 2nd (7/7) BNT162b2-mRNA (7/7) 2 (2–4)
Chest pain (7/7)
Fatigue (3/7)
4 Rosner et al.9 7 7:0 24 (19–39) Chest pain (7/7) Endomyocardial biopsyb Resolved (7/7) 1st (2/7) BNT162b2-mRNA (5/7) 3 (2–7)
Fever (2/7) 2nd (5/7) mRNA-1273 (1/7)
Ad26.CoV.S (1/7)
5 Snapiri et al.11 7 7:0 16.8 (16.2–17.6) Chest pain (7/7) Not done Resolved (7/7) 1st (1/7) BNT162b2-mRNA (7/7) 2 (1–3)
Fever (1/7) 2nd (6/7)
6 Kim et al.4 4 3:1 30 (23–70) Chest pain (4/4) Not done Resolved (4/4) 2nd (4/4) BNT162b2-mRNA (2/4) 2.5 (1–5)
Fatigue (3/4) mRNA-1273 (2/4)
Fever (3/4)
7 Mansour et al.6 2 1:1 23 (21–25) Chest pain (2/2) Not done Resolved (2/2) 2nd (2/2) mRNA-1273 (2/2) 1.5 (1–2)
Fever (1/2)
8 Verma et al.10 2 1:1 43.5 (42–45) Chest pain (2/2) Endomyocardial biopsy Resolved (1/2) 2nd (2/2) BNT162b2-mRNA (1/2) 12 (10–14)
Autopsy Died (1/2) mRNA-1273 (1/2)
9 Ammirati et al.3 1 1:0 56 Chest pain Not done Resolved 2nd BNT162b2-mRNA 3
10 Kim et al.12 1 1:0 24 Chest pain Not done Resolved 2nd BNT162b2-mRNA 1
11 Present study 1 1:0 22 Chest pain Autopsy Died 1st BNT162b2-mRNA 5
Fatigue

Sx = symptom, M = male, F = female.

aThe authors reported time to symptom onset as hours with mean (range); bOne patient underwent endomyocardial biopsy in each study, but myocardial inflammation was not found.