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. 2021 Oct 18;9(10):e002919. doi: 10.1136/jitc-2021-002919

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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Changes in immune cell subsets and specific immune markers in bone marrow aspirates by Nanostring RNA expression profiling after tremelimumab and durvalumab. A) Scatter plots of immune cell phenotypes in bone marrow aspirates pre- and post-treatment with tremelimumab and durvalumab. B) Left: Volcano plot of differentially expressed genes (Log₂ FC>1.2 and p-value <0.05) pre-and post-treatment. (Pre in blue, n=11; post in red, n=10). Right: Scatter plots showing expression of specific immune markers pre- and post-treatment.