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. 2021 Oct 6;46(6):250. doi: 10.3892/or.2021.8201

Figure 4.

Figure 4.

Effects of MBD2 and EZH2 knockdown separately or simultaneously on CRC cell migration. Wound healing assay was used to detect knockdown of MBD2 and EZH2 separately or simultaneously on (A) SW480 and (B) HCT116 cell migration. The effects of knockdown of MBD2 and EZH2 separately or simultaneously on migration of SW480 cells were statistically analyzed following wounding at 24 h (C) and 36 h (D) The effects of knockdown of MBD2 and EZH2 separately or simultaneously on migration of HCT116 cells were statistically analyzed following wounding at 24 h (E) and 36 h. (F) *P<0.05, **P<0.01, ***P<0.001 vs. si-NC. CRC, colorectal cancer; MBD2, methyl-CpG binding domain protein 2; EZH2, enhancer of zeste homolog 2.