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. 2021 Oct 6;46(6):250. doi: 10.3892/or.2021.8201

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Copyright: © Xie et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 6. — Effect of the knockdown of MBD2 and EZH2 on the apoptosis of CRC SW480 and HCT116 cells. Flow cytometry was used to detect the effect of the knockdown of MBD2, (A) EZH2, (B) MBD2 and EZH2 (C) and control group si-NC (D) on apoptosis of SW480 cells. Flow cytometry was used to detect the effect of the knockdown od MBD2, (E) EZH2, (F) MBD2 and EZH2 (G) and control group si-NC (H) on apoptosis of HCT116 cells. Statistical analysis of the knockdown of MBD2 and EZH2 on the percentage of apoptotic cells of SW480 (I) and HCT116. (J) *P<0.05, **P<0.01, ***P<0.001 vs. si-NC. CRC, colorectal cancer; MBD2, methyl-CpG binding domain protein 2; EZH2, enhancer of zeste homolog 2.