The Systematic Monitoring of EEG in Asphyxiated Newborns During Rewarming After Hypothermia Therapy (SMART) study started 1 year following the Optimizing Cooling (OC) trial initiation and 16 of 18 OC trial sites participated in SMART. A total of 120 infants (82%) met the predefined inclusion criteria of completed ambulatory electroencephalography (aEEG) during rewarming with good impedance and 112 (90%) had complete data for death or disability.
aThe SMART study period began in January 2012.
bOther reasons included parent withdrawal of consent, lack of access, clinical aEEG in place, and poor impedance.