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. 2021 Oct 14;14:5291–5304. doi: 10.2147/JIR.S309457

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© 2021 Chen et al.

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Capsaicin (CAP) pretreatment inhibits the activation of PI3K/AKT/mTOR signaling in lipopolysaccharide (LPS)-induced acute lung injury. (A) Western blot analysis of p-PI3K, PI3K, p-AKT, AKT, p-mTOR, and mTOR expression in lung tissue. GAPDH was used as the loading control. (B–D) Quantitative analysis of (A). Results are representative of three independent experiments and data are presented as mean ± SD (n = 6–8 for each group). **p < 0.01 versus the vehicle group; ^#p < 0.05 and ^##p < 0.01 versus the LPS group.