Fig 3.

Proteomic differences in skin associated with perioperative oxygen delivery. (a) Oxygen delivery (DO₂) expressed as percentage of preoperative DO₂ (measured before induction of anaesthesia). P-values refer to comparison between subjects with normal vs low DO₂ over each hour during the 6 h intervention period after surgery. (b) Identification of 14 proteins that were differentially expressed after surgery in non-DO₂ achievers and DO₂ achievers (median confidence score 63.7 [27.1–128.5]). Heatmap data are shown for relative changes for within-protein comparisons, for subjects with normal vs low DO₂ during trial intervention.