Skip to main content
. 2021 Oct 8;24(6):839. doi: 10.3892/mmr.2021.12479

Table III.

Mono amino oxidase inhibitors (120).

Drug Selectivity FDA approval Common adverse effects >10% incidence Administration in pregnancy Interactions
Isocarboxazide Non-selective MAOIs 1959 Weight gain, chills orthostatic hypotension, forgetful, headache, sexual dysfunction, lethargy, constipation, dizziness, serotonin syndrome No data Salmeterol, trazodone, alcohol, citalopram, zolpidem, duloxetine, amitriptyline, venlafaxine, escitalopram, phenelzine and lisdexamfetamine.
Phenelzine 1961 Dizziness, confusion, chills, tremors, drowsiness, weakness, insomnia and dry mouth No data Citalopram, duloxetine, dextromethorphan, meperidine, fentanyl, tryptophan, lisdexamfetamine and vilazodone.
Selegiline 1998 Orthostasis, dizziness, nausea and abdominal pain No Duloxetine, escitalopram, meperidine, rasagiline, bupropion and amphetamine
Tranylcypromine Selective MAO-A inhibitors 1961 Anxiety, dizziness, weakness and constipation. No data Duloxetine, citalopram, selegiline, phenelzine, escitalopram, paroxetine, pseudoephedrine and lisdexamfetamine.
Brofaromine 1995 Tremor, sleep disorders, dry mouth and hypotension No data Warfarin, amantadine, amitriptyline, apomorphine, benzodiazepine, bupropion, dobutamine, duloxetine and ethanol.

MAO, mono amino oxidase.