Table IX.

Noradrenaline and dopamine reuptake inhibitors (169).

Drug	FDA approval	Common adverse effects >10% incidence	Administration in pregnancy	Contraindications/interactions
Bupropion	1985	Anxiety, restlessness, dry mouth, hyperventilation, irritability, shaking, irregular heartbeats, trouble sleeping and ringing in the ears.	Only if the potential benefit outweighs the potential risk to the fetus	Epilepsy, conditions that lower the seizure threshold (anorexia nervosa, bulimia nervosa, benzodiazepine or alcohol withdrawal), MAOIs, liver damage, kidney disease, severe hypertension, in children and adolescents (risk of suicidal attempt). Drug-drug interactions: acetaminophen, diphenhydramine Drug-food/beverage interactions: grapefruit juice