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Pyroptosis in HPDE6C7 cells as observed by Hoechst/PI staining (magnification, ×50). (A) HPDE6C7 cells were treated with CAE at 12, 24 and 48 h. (B) Following TRAF6 overexpression, HPDE6C7 cells were treated with CAE. 12H, CAE treatment for 12 h; 24H, CAE treatment for 24 h; 48H, CAE treatment for 48 h; CAE, caerulein; TRAF6, tumor necrosis factor receptor-associated factor 6.
