TABLE 5.
Effect of variables on MoCA in three linear regression models among female patients.
| Variable | β (95% CI) p-Value | ||
|
|
|||
| Non-adjusted | Adjust I | Adjust II | |
| Age | −0.30 (−0.59, −0.01) 0.0482 | −0.22 (−0.51, 0.08) 0.1604 | −0.01 (−0.40, 0.37) 0.9397 |
| Fazekas | |||
| 1 | 0.44 (−3.34, 4.21) 0.8218 | 1.41 (−2.30, 5.11) 0.4603 | 1.54 (−2.60, 5.68) 0.4699 |
| 2 | −3.48 (−7.06, 0.10) 0.0623 | −1.72 (−5.36, 1.92) 0.3599 | −2.53 (−7.40, 2.33) 0.3145 |
| 3 | −3.92 (−9.82, 1.97) 0.1983 | −0.34 (−6.72, 6.04) 0.9179 | −3.10 (−10.07, 3.86) 0.3887 |
| HBP | −2.78 (−7.23, 1.66) 0.2251 | −1.33 (−5.78, 3.11) 0.5592 | −0.26 (−4.96, 4.45) 0.9159 |
| Diabetes | −0.80 (−3.83, 2.22) 0.6040 | 0.63 (−2.34, 3.61) 0.6781 | −1.71 (−4.94, 1.52) 0.3057 |
| CHD | −1.82 (−5.32, 1.69) 0.3150 | −0.55 (−4.10, 2.99) 0.7614 | −1.85 (−5.61, 1.91) 0.3421 |
| Stroke | −6.34 (−10.24, −2.44) 0.0024 | −5.35 (−9.95, −0.74) 0.0276 | −4.29 (−9.16, 0.58) 0.0930 |
| SFR >0.05 | −5.43 (−8.13, −2.72) 0.0003 | −5.80 (−8.72, −2.88) 0.0003 | −5.54 (−8.78, −2.30) 0.0020 |
| Creatinine > = 111 | 4.43 (−2.07, 10.93) 0.1874 | 5.05 (−1.38, 11.47) 0.1309 | −3.14 (−14.19, 7.90) 0.5804 |
| Uric acid > = 428 | −1.29 (−5.17, 2.60) 0.5190 | −0.67 (−4.68, 3.35) 0.7463 | −3.32 (−10.13, 3.49) 0.3460 |
| α−HBDH > = 182 | −0.88 (−4.32, 2.57) 0.6210 | −0.25 (−3.76, 3.25) 0.8881 | 1.25 (−4.59, 7.09) 0.6777 |
| HSCRP > = 3 | −1.05 (−4.68, 2.58) 0.5743 | −1.57 (−5.17, 2.02) 0.3959 | −2.39 (−9.89, 5.11) 0.5368 |
| TC > = 5.2 | −0.41 (−4.17, 3.34) 0.8298 | −1.08 (−4.91, 2.75) 0.5829 | 0.44 (−5.59, 6.47) 0.8876 |
| TG > = 1.7 | 0.47 (−2.98, 3.93) 0.7886 | −0.37 (−3.85, 3.12) 0.8373 | −4.02 (−11.05, 3.00) 0.2691 |
| HDLC > = 1 | 0.67 (−3.22, 4.57) 0.7363 | 0.11 (−3.79, 4.01) 0.9547 | 0.29 (−5.17, 5.75) 0.9178 |
| LDLC > = 3.4 | −0.83 (−5.33, 3.68) 0.7204 | −1.77 (−6.21, 2.66) 0.4377 | −4.93 (−13.16, 3.30) 0.2487 |
| APOA > = 1.6 | −0.57 (−3.95, 2.80) 0.7403 | −0.34 (−3.97, 3.29) 0.8554 | −2.42 (−8.33, 3.49) 0.4284 |
| APOB > = 1.25 | 0.58 (−4.23, 5.40) 0.8133 | −0.44 (−5.22, 4.34) 0.8574 | −3.95 (−10.91, 3.00) 0.2728 |
Adjusted model 1 was adjusted for risk factors of CSVD (Fazekas; age; hypertension; diabetes; coronary heart disease; stroke). Adjusted model 2 was adjusted for all covariables.
HBP, hypertension; CHD, coronary heart disease; SFR, Sylvian fissure ratio; α-HBDH, α-hydroxybutyrate dehydrogenase; HSCRP, high-sensitivity C-reactive protein; TC, total cholesterol; TG, total triglyceride; HDLC, high-density lipoprotein cholesterol; LDLC, low-density lipoprotein cholesterol; APOA, apolipoprotein A; and APOB, apolipoprotein B.