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Androgens in lung cancer. Androgen receptor signaling induces cyclin D1 expression, tumor growth, and macrophage M2 polarization. There is also evidence that miR-224-5p negatively targets AR causing a decrease in tumor incidence and growth. (A color version of this figure is available in the online journal.)
AR: androgen receptor; M2: Macrophage M2 polarization; T: testosterone.
