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. Author manuscript; available in PMC: 2022 Mar 15.
Published in final edited form as: Cancer Res. 2021 Sep 15;81(18):4874–4885. doi: 10.1158/0008-5472.CAN-20-3898

Figure 1. SHEAR platform.

Figure 1.

(A) Schematic of the SHEAR optical set up. (B) Representative speckle frames acquired at 4 time points. (C) A representative trace of temporal speckle intensity fluctuations from a normal adipose breast tissue. (D) Cross-correlation of speckle fluctuations provides the speckle intensity autocorrelation, g2(t), from which the mean square displacement (MSD) of particles is deduced (inset). (E) Substituting the MSD in the GSER returns ∣G*(ω)∣, G'(ω) and G"(ω) (Supplementary Method 1).