Fig. 3.

Plasma levels of IL-18 (A), IL-18bp (B) and the C IL-18/IL-18bp ratio during follow-up. Plasma levels of IL-18 and IL-18bp at admission and follow-up (FU, 48 h after admission) were available in 22 patients with HIV infection without malaria and in patients with falciparum malaria without (n = 29, of which 14 with severe disease) and with HIV infection (HIV + M, n = 48 of which 33 with severe disease). Lines in the scatter plot represent the median and 25–75th percentiles. *p < 0.05, ***p < 0.001 versus levels at admission