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. 2021 Oct 18;20:209. doi: 10.1186/s12933-021-01399-z

Table 3.

The performance of the different models compared to the index eGFR model on the prediction of all-cause mortality

C-index P IDI (95% CI) P NRI (95% CI) P
Index eGFR 0.629 (0.574, 0.684) Reference Reference
Mean eGFR 0.619 (0.566, 0.673) 0.846 − 0.003 (− 0.010, 0.002) 0.159 − 0.155 (− 0.336, 0.097) 0.246
SD of eGFR 0.593 (0.541, 0.644) 0.800 − 0.008 (− 0.022, 0.005) 0.199 − 0.154 (− 0.282, 0.011) 0.060
Index eGFR + SD of eGFR 0.671 (0.620, 0.723)  < 0.001 0.008 (0.002, 0.023) 0.007 0.141 (0.017, 0.252) 0.027

CI  confidence interval, IDI  integrated discrimination improvement, NRI  continuous net reclassification improvement, eGFR  estimated glomerular filtration rate, SD  standard deviation