Fig. 4.

LINC00337 interplays with miR-1285-3p directly. A The binding sequence of LINC00337 with miR-1285-3p, miR-1304-5p, miR-492, miR-1273a, miR-5095, and miR-1273 g-3p, as predicted by RegRNA 2.0. B Detection of LINC00337 using qRT-PCR in samples pulled down by biotinylated LINC00337 and a negative control probe. C Examination of miR-492, miR-1285-3p, miR-1304-5p, miR-1273a, miR-5095, and miR-1273 g-3p in the same sample was reduced by biotinylation of LINC00337 and the NC probe. D The level of miR-1285-3p in 46 pairs of lung adenocarcinoma and para-tumor tissues. E The expression levels of miR-1285-3p in cells transfected with either shRNA or LINC00337 were evaluated by qRT-PCR. Data represent the mean ± SD; ** P < 0.01, ***P < 0.001