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. 2021 Oct 19;21:1124. doi: 10.1186/s12885-021-08821-5

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — HRCT and pathological characteristics of a 51-year-old female patient with acinar-predominant adenocarcinoma. a CT image showed a mGGN in the right upper lobe with lobulated border, spiculated margin (black arrow), and pleural indentation, mean CT value was − 464.1HU, as measured using Freehand ROI (irregular white ring) as large as possible on axial view. b CT image showed that chordal distance (thick line)/chord length (thin line) of Deep lobular margin was 0.89 (7.3 mm/8.2 mm). vascular and bronchial changes (black arrow) were showed. c Photomicrograph of histopathologic specimen showed acinar pattern is consisting of round to oval shaped malignant glands (black arrow) invading fibrous stroma (white arrow). (Hematoxylin-eosin stain; original magnification, × 100)