Table 2.

HDV genotypes and their geographical distribution

Genotype	Geographical location	Clinical features
1	Europe, North America and South Asia,Central and Northern Asia, eastern Mediterranian, and Middle East	Variable course
2	Yakutia region (Russia), Taiwan (China), and Japan	Higher rate of remission than genotype 1
3	Amazon Basin	More severe, earlier onset of HCC, and outbreaks of lethal acute liver failure
4	Miyako Island (Japan), Taiwan (China)	Variant on the Miyako Islands associated with greater progression to cirrhosis than in Taiwan
5	Africa, Europe (migrants from Africa)	More associated with HCC than genotype 1 and other African genotypes Better prognosis with fewer episodes of hepatic decompensation
6,7,8	Africa, Europe (migrants from Africa)	Few data